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DISSOLVED OXYGEN

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     SUMMARY:  Seawater is collected from known depths using 
     CTD-rosette sampling protocols.  Subsamples are drawn 
     into precalibrated iodine flasks and dissolved oxygen is 
     chemically bound by the formation of a manganese (III) 
     hydroxide floc.  The floc is subsequently dissolved under 
     acidic conditions which stochiometrically converts the 
     original dissolved oxygen (DO) oxidizing equivalents to 
     triiodide.  The latter is quantitatively titrated with 
     sodium thiosulfate to a potentiometric end-point using 
     a high-precision computer-controlled titration system.
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1.  Principle
  
    The oxygen content of seawater is a fundamental measurement in 
oceanography providing information which can elucidate water mass 
movements, net primary productivity, atmosphere-ocean interactions 
and carbon remineralization processes.  The oxygen content of a 
seawater sample is largely determined by a balance between:  (a) 
the exchange of atmospheric oxygen with the upper mixed layer, (b)
net increases due to photosynthetic processes and (c) net decreases 
due to respiratory demands and heterotrophic processes.  From an 
oceanographic perspective, the measurement of dissolved oxygen is a 
parameter of fundamental importance.  

    In this procedure, a divalent manganese solution and a strong 
alkali are added to the water sample which results in the formation 
of a floc (1).  In the presence of oxygen the manganese II is 
oxidized to manganese III (2).  On subsequent acidification (1 < pH < 2.5), 
the manganese hydroxide floc dissolves, and I2 is produced in 
stoichiometric proportion to the original O2 concentration (3).  
The iodine, in the form of triiodide (4), is titrated with a 
standardized thiosulfate solution (5), and the oxygen content is 
calculated from the quantity of thiosulfate consumed.

  (1)	Mn2+ + 2OH ---------- Mn(OH)2
  (2)	2Mn(OH)2 + ½O2 + H2O ---------- 2Mn(OH)3
  (3)	2Mn(OH)3 + 2I- + 6H+ ---------- 2Mn2+ + I2 + 6H2O
  (4)	I2 + I- ---------- I3-
  (5)	I3- + 2S2O32- ---------- 3I- + S4O62-


2.  Precautions

    It is extremely important to prevent contamination of the 
sample with atmospheric oxygen during sampling, fixation and storage.  
Drawing tubes and sample flasks must be free of bubbles (3.1 and 
3.2.1), as must the autopipette system which dispenses the reagents 
(3.2.2).  If the water samples cool significantly or the seal dries 
during storage, air can infiltrate the flask.  The rims of the flasks 
are filled with seawater and the samples are stored in a location 
where temperature fluctuations are minimized (3.4).

    The solubility of oxygen in seawater is temperature-dependent and 
deep samples may warm up as they are brought to the surface (i.e. 
through the thermocline).  It is therefore necessary to measure the 
temperature in the Niskin bottle at the time the sample is drawn in 
order to calculate the oxygen concentration in situ (3.3).  Oxygen 
samples are always the first samples drawn from the Niskin bottles.


3.  Field Sampling

3.1. Sample collection

  3.1.1. Subsamples are drawn as soon as the rosette arrives on deck.  
         DO samples are the first samples drawn from the water 
         sampling bottle. 

  3.1.2. The drawing tube is flushed with sample and any bubbles are 
         displaced.  The tube is then inserted (with water flowing) 
         almost to the bottom of the sample flask.  Care is taken to 
         avoid creating turbulence in the flask in order to minimize 
         the intrusion of atmospheric oxygen.   

  3.1.3. The flask is overflowed with two to three volumes of sample.  
         With the sample flowing, the tube is slowly withdrawn from 
         the flask so that the bottle remains brimful when the tube 
         is completely withdrawn.

3.2. Sample fixation 

  3.2.1. Before fixing the sample, the iodine flask is carefully 
         examined for any bubbles that may have adhered to the walls.  
         If any bubbles are present, the sample is discarded and drawn 
         again.    

  3.2.2. Immediately after examining the flask, the two fixing 
         reagents (manganous chloride and alkaline iodide) are added 
         simultaneously using two 1 ml autopipettes mounted side-
         by-side and activated by a single injection lever arm.  
         Care is taken so that bubbles are not added in this process.  
         The pipette tips are positioned at least 3 cm below the 
         surface of the sample, the lever arm is pressed slowly and 
         gently and released while the pipette tips are still 
         submerged, and the pipettes and tubing are checked frequently 
         for bubbles.   

  3.2.3. The glass stopper is carefully inserted and the flask is 
         shaken vigorously for at least 20 seconds with a rapid wrist 
         action (it is extremely important that the floc be dispersed 
         throughout the flask).     

3.3. Sample temperature
  3.3.1. The temperature of the water in the Niskin bottle is measured 
         and recorded immediately following sample collection and 
         fixation.  This is accomplished by a second person to 
         reduce the time interval between sampling and temperature 
         determination.

  3.3.2. An insulated holding container is rinsed thoroughly and 
         filled with the sample.  The temperature is then measured 
         with a NBS traceable quick-response digital thermometer. 

  3.3.3. In situ temperature is measured at the time of bottle trip 
         using a calibrated thermistor (see Chapter 4).

3.4. Storage

  3.4.1. Approximately 20 minutes after the samples are collected, 
         the sample bottles are shaken again to resuspend the floc.  
         The flared mouth of the flask is then filled with seawater 
         and bottles are stored in a cool location where temperature 
         fluctuations are minimized.              


4.  Analysis

4.1. Computer controlled potentiometric titration 

    The computer program (DO05HOT.BAS) is written in GW Basic and 
located in the DO subdirectory on the AT 286 hard drive.  This 
program interfaces and operates the Dosimat (model 665) and pH 
meter (Orion model 720A or EA940).  The program parameters are 
chosen to optimize the equivalence point determination based on 
the computer controlled addition of µl quantities of titrant.  The 
titration time is approximately 10 minutes per sample, which is a 
function of the response time of the electrode and the preset 
electrode stability criteria.  The titration time is minimized by 
the manual addition of titrant by the operator until the color of 
the sample is a very light yellow (almost clear).  At this point 
the computer-controlled functions are enabled.  The computer 
terminates the titration when the end point criteria are met.  
The following steps outline the Incremental mv Titration program 
operation:

   1.  After the computer has booted and all peripheral instruments 
       are connected to the computer and turned on, change 
       directories to C:\DO.  The titration program and GWBasic 
       reside here.  To initialize the program, type "GWBASIC DO05HOT" 
       and return.

   2.  If the system is ready to go (i.e., all connections are "OK" 
       and all peripherals are working) the program will list a 
       description of the task keys available.  When you are done 
       with this screen, press return.

   3.  You will be presented with the option to load preset parameters 
       into the program.  For work at Sta. ALOHA you should answer "Y" 
       or "y".

   4.  Next you will be asked to input the name of the file containing 
       the parameters.  The default answers are ALOHA05 and C:\DO.  
       These default answers should be accepted for routine work at 
       Sta. ALOHA.

   5.  The program will list the default operational parameters which 
       have been found to optimize the sensitivity and precision of 
       the equivalence point determination at Sta. ALOHA and will 
       prompt you to either accept the default values or change them.  
       In most instances the statement is self-explanatory. 

                       Statement                   Comments

      Sodium thiosulfate normality (N) = 0.10      This is the standardized 
			                           normality of the Na2SO3 
                                                   titrant.  This together 
                                                   with the change in mv and
                                                   volume added determines 
                                                   the slope.

      Buret size (ml) = 5                          Capacity of the Dosimat 
                                                   buret on the exchange
                                                   unit.

      Titration increment size (ml) = 0.02         This is the initial 
                                                   volume of titrant added 
                                                   before the first slope 
                                                   criteria is enabled.

      Preadd volume (ml) = 0                       This is set at 0 since 
                                                   we add the preadd manually.

      Total vol. of titrant (ml) = 4               This is one of the three 
                                                   titration end point 
                                                   criteria.  If 4 ml of 
                                                   titrant is reached, the 
                                                   titration is terminated.

      Stop potential (mv) = 100                    This is the second of the 
                                                   three end point criteria.  
                                                   If the potential reaches 
                                                   100 mv, the titration is
                                                   terminated.

      Electrode drift time (sec/.2mv) = 5          Criteria for electrode 
                                                   stability.

      First slope increment change (mv/meq) =      This is a calculated 
                                                   value which controls the
                                                   reduction in titrant 
                                                   increment size (300 mv/
                                                   titrant normality).

      Second slope increment change (mv/meq) =     calculated (750 mv/titrant 
                                                   normality) 

      Third slope increment change (mv/meq) =      calculated (3000 mv/titrant 
                                                   normality) 

      First increment volume change (ml) = .01    Titrant volume increment 
                                                  when first slope criteria
                                                  is enabled.

      Second increment volume change (ml) = .002  Titrant volume increment 
                                                  when second slope criteria
                                                  is enabled.

      Third increment volume change (ml) = .0005  Titrant volume increment 
                                                  when third slope criteria
                                                  is enabled.

   6.  If you wish to accept these values (which you should for routine 
       work at Sta. ALOHA), then enter a "Y" or "y" and return.  If you 
       do not want to accept the default parameters enter a "N" or "n".
       You will have to input all values except those calculated.
   7.  Next you will be asked to input:

      (a)  the date of analysis
      (b)  the pH meter model used
      (c)  if you have a printer connected to the computer
      (d)  if you want a detailed or summarized printout of the 
           titrations (use summarized for routine work at Sta. ALOHA).
      (e)  if you want an alarm to be activated at the end of each run
      (f)  the path of data storage (C:\DO\HOT##)
      (g)  the sample name.  This is an 8 character max file name and 
           for standardization purposes the following convention is 
           used.  For blanks and standards an alphanumeric designation 
           is used which represents the date and sample type.  For 
           samples, an alphanumeric system is also used which 
           represents the iodine flask number and the HOT cruise 
           number (see examples below, assume the date of the analysis 
           is 3/25/92 for these examples):

           Reagent Blank                3252bl1 (this creates a prn
                                        file with the name 3252bl1.prn)

           Primary KIO3 Standard        3252std1 (if you run more than 
                                        1 std then number sequentially)

           CSK Certified KIO3 Standard  3252csk1

           DO Sample                    1H36 (iodine flask number 
                                        followed by HOT cruise number).

           DO Sample Backtitrated       1BH36

           Different DO Sample          1AH36
           analyzed in a previously 
           used flask

      (h)  your name or ID

   8.  At this point a statement will appear on the screen instructing 
       you that the Dosimat is now in the manual titration mode and 
       to titrate your sample to a pale yellow color.  To reduce the 
       titration time, manually titrate to a very pale yellow (almost 
       clear), then press "x".

   9.  From this point on the computer controls the titration, 
       adjusting the volume of titrant added in response to the 
       slope criteria.  The titration is terminated when one of 
       three events occurs.  Either the volume of titrant or mv 
       criteria is reached or the calculated slope increases four 
       consecutive times.

  10.  At this point, the results are printed out and you are 
       prompted to make any comments which are specific to that 
       sample.  Record any problems, observations or concerns.  
       This is a great help in interpreting the data.  Entering 
       return will close that file and you will be prompted if you 
       would like to run another sample.  By entering "Y" or "y" 
       the process begins again.  If you do not want to run any 
       more samples press "N" or "n" and you will see "ok".  Type 
       "system" to return to the C: prompt.  Type "run" to start 
       the program again.  Normally the program is not terminated 
       until the end of the cruise.  If all of the samples have 
       been run but more are to be collected, do not terminate 
       the program (i.e., do not enter "n"; leave it as is).

   Other concerns:

   (a)  Backtitrating

   The program adds incremental volumes of titrant to the sample 
   based on selected slope criteria.  If the operator gets too close 
   to the equivalence point or passes it, during the manual titration 
   step, then the program will not reach its end point criteria and 
   will continue to run.  To avoid this, check the mv reading.  For 
   our samples this reading should be approximately 320-360 mv at the 
   end of the manual addition.  If you find that you have titrated 
   just past this point, go ahead and enable computer controlled 
   titration and observe 3 or 4 cycles checking the slope.  It should 
   decrease to a minimum value (~-500,000 to -900,000), and then 
   increase.  If it initially increases and the mv readings are below 
   300 mv then you have gone too far.  In this case, press F5 and add 
   volumetrically a known amount of primary standard.  Ideally, you 
   want to add an amount which is equivalent to the normal manual 
   addition end point.  I have found this to usually be around 100-
   200 µl, depending on how far you went over or how long the program 
   ran.  The program will have continued to add 20 µl if you passed 
   the end point during the manual addition.  If you walk away and 
   come back 1/2 hr later, it will still be adding titrant at 20 µl 
   every 2-3 minutes.  In this case the 200-300 µl of titrant have 
   been added.  Therefore, you need to add enough primary standard 
   to equal this amount plus an amount equal to the manual addition 
   end point.  Our primary standard is about 0.025 N and the titrant 
   about 0.05 N so you would need to add 400-600 µl of primary 
   standard to equal the added titrant, plus approximately 100 µl 
   to reach the manual addition end point.  From this point, the 
   program should function properly.

   (b)  Interrupting an analysis in progress

   If for some reason you need to interrupt an analysis, you can do 
   so by pressing F1.

   (c)  Restarting an interrupted analysis

   After the buret refills, the program will prompt you whether you 
   want to run another sample.  Continue in the normal manner.

   (d)  Volumetric delivery of standards

   To obtain the maximum precision and accuracy it is critical to 
   deliver the primary standard in a manner which is accurate and 
   reproducible.  At sea and in the laboratory we use class A 
   volumetric pipets which have been gravimetrically calibrated.  
   At the 5000 µl range, these glass pipets are accurate to within 
   +4.0 µl (0.08%) with a precision of +2.5 µl (0.05%).  This is 
   equal to the precision of the Dosimat within the delivery range 
   of 500-3000 µl.  To obtain this precision it is necessary to be 
   very reproducible in the delivery operation.  A technique which 
   produces good results is outlined below:

      1)  Fill the pipet past the calibration mark and slowly deliver 
          the contents into the container until the meniscus is level 
          with the mark.

      2)  Invert the pipet and wipe off any excess solution from the 
          tip and barrel (the level of the solution within the pipet 
          will be below the tip at this point).
      3)  Invert again and touch the pipet tip to the sample vessel 
          wall.  Release finger pressure and allow pipet to drain.  
          After the pipet has drained keep the tip against the vessel 
          wall for an additional 15-20 seconds.

      4)  Remove pipet and rinse any solution that may be on the vessel 
          wall into the sample with DDW.

   To maintain accuracy and precision it is necessary to have an 
   absolutely clean pipet where none of the delivered solution clings 
   to the pipet walls.  It is also good practice to rinse the pipet 
   with the filling solution prior to filling (unless this is the 
   first use of the pipet).

4.2. Reagent blank determination  

   The reagent blank is determined by adding the fixing reagents in 
   reverse order and titrating a known volume of primary standard 
   three separate times in the same flask.  The volume of the first 
   titration includes the equivalents of primary standard added plus 
   any oxidizing or reducing substances in the reagents (V1); the 
   second titration should theoretically be equal to the equivalents 
   of primary standard only (V2).  However, it has been our experience 
   that we rarely observe an obvious difference between V1 and V2 
   which could be attributed to the reagents and not a variable end 
   point estimation or pipetting.  To help quantify this relationship 
   we have added a third aliquot titration (V3), which again should 
   be equivalent to only the primary standard.  A statistical 
   comparison between the estimates of |V1-V2| and |V2-V3| is 
   performed to determine whether a significant blank exists.

   Fill an iodine flask with distilled water and add in the following 
   order, mixing after each addition, 1 ml of sulfuric acid reagent 
   (10 N), 1 ml alkaline iodide reagent (4 M sodium iodide in 8 N 
   sodium hydroxide), and 1 ml manganese chloride reagent (3 M).  
   [Care must be taken to dispense the reagents below the blank 
   solution surface or in such a manner as to ensure that no 
   precipitate forms in the neck of the flask.  If this occurs, a 
   high blank will be encountered if the precipitate subsequently 
   dissolves in the acidified blank solution during the titration 
   step.  This is especially prevalent when using the redox 
   electrode which displaces a larger volume of sample into the neck 
   of the flask.]  Add 1.0 ml of 0.01 N potassium iodate from a 
   precalibrated glass class A volumetric pipette.  Titrate 
   manually, with adequate stirring, to a very pale yellow color, 
   enable computer operation of the titration and run to completion.  
   Record the volume at the equivalence point as V1.  Add a second 
   1.0 ml aliquot of potassium iodate to the flask and titrate as 
   above.  

   Record as V2 the sum of the volume at the equivalence point and 
   the residual titrant from the first titration (this is equal to 
   the total amount of titrant added minus the volume of titrant 
   at the equivalence point).  Add a third 1.0 ml aliquot of 
   potassium iodate, titrate and record volume as V3 in the same 
   manner as V2.  Repeat this procedure a minimum of 3 times or 
   until a clear pattern is established.

4.3. Standardization of the thiosulfate titrant

   Prepare a blank solution as outlined section 4.1.  Add a known 
volume (at least 5 ml) of potassium iodate primary standard (usually 
0.02 N). It is necessary to know the volume added and the normality 
of the potassium iodate to the highest degree of accuracy that is 
reasonably possible.  Therefore, class A volumetric pipets which 
have been gravimetrically calibrated should be used and the potassium 
iodate should be thoroughly dried, weighed in large aliquots relative 
to the sensitivity of the balance to reduce weighing errors, and the 
final primary standard volume determined gravimetrically.  Titrate as 
outlined above.  Since precision is usually increased with increasing 
number of titrations, it is our general practice to titrate 3-7 
replicates at the beginning and end of each analytical run.  In 
addition to these, we typically run 1-4 standards per day since our 
samples are analyzed at sea over a 3-4 day period.

4.4. Calculate the concentration of thiosulfate working solution 
using the following relationship: 

                           VT * NT = VI * NI

where: VT= the blank corrected volume of thiosulfate used to 
           reach the end-point 
       NT= the normality of thiosulfate solution
       VI= the volume of potassium iodate added
       NI= the normality of potassium iodate solution

4.5. Sample titration

    Remove the ovelying seawater seal and remove the stopper.  Add 
1 ml of sulfuric acid reagent (10 N), and carefully slip a clean 
teflon-coated magnetic stir bar into the flask.  Place the flask 
on a magnetic stirrer, insert the clean redox electrode and titrant 
delivery tube.  Titrate as outlined above.  Record the presence of 
bubbles or any unusual aspects of the titration or sample condition 
in the comment section.  Rinse electrode and titrant delivery tube 
with DDW and repeat above procedure for the next sample.


5.  Calculations

    Calculate the DO concentration using the following formula:

                                  (Vt-Vb) * Nt * E
                     µmol O2 l-1 = ________________ - RDO
                                      (Vf - Vr) 

    where: Vt= volume of titrant (µl)
           Vb= volume of blank (µl)
           Nt= normality of titrant (µeq µl-1)
            E= 0.2500 (µmol O2 µeq-1)
           Vf= volume of flask (l)
          RDO= dissolved oxygen content of the reagents = (0.804 * 0.14)/Vf 
           Vr= volume of fixing reagents (l)

    This value is derived from Carpenter 1965 (i.e., DO content 
of fixing reagents when 1 ml of each reagent is used in 140 ml of 
sample equals 0.018 ml O2 l-1).


6.  Precision and Accuracy

    The method as outlined above is capable of a precision of 0.1% 
or less (as defined by the coefficient of variation for triplicate 
samples).  The accuracy of the Winkler titration procedure, when 
the Carpenter modifications are employed, has been determined to be 
0.1% (Carpenter, 1965a,b).

    Currently, we are using a high quality commercially prepared 
potassium iodate certified reference standard to independently 
assess the accuracy of our potassium iodate primary standard 
normality.  A batch of primary standard is prepared and the 
theoretical normality normalized to the certified primary 
standard value.  Our primary standard is periodically checked 
against the certified standard until the batch or lot is exhausted.


7.  Equipment

    5 ml Dosimat titrator (Brinkmann)
    calibrated iodine titration flasks
    teflon-coated magnetic stir bars and retriever
    squirt bottle with deionized distilled water (DDW)
    reagent dispensers
    magnetic stir plate
    calibrated volumetric pipettes and flasks


8.  Reagents
  
    Manganese chloride reagent (3 M) 
       Dissolve 600 g of manganese chloride tetrahydrate (MnCl2.4H2O) 
       in 800 ml distilled water and make up to 1 liter in a 
       volumetric flask.

    Alkaline iodide reagent 
       Dissolve 320 g sodium hydroxide (NaOH) in 500 ml distilled 
       water and, separately, dissolve 600 g sodium iodide in 500 
       ml distilled water.  Mix the he two solutions 1:1, by volume.

    Sulfuric acid reagent (10 N)
       Mix 280 ml of concentrated sulfuric acid into distilled water 
       using a 1 liter volumetric flask

    Sodium thiosulfate reagent (0.05 N)
       Dissolve 24.82 g of reagent grade sodium thiosulfate (Na2S2O3.
       5H2O and make up to one liter with distilled water.  Determine 
       exact normality as described under 4.3 above.

    Potassium iodate reagent (0.025 N)
       Dissolve 0.8918 g of dry (100°C, 2 hours) KIO3 into 800 ml 
       distilled water and bring up to 1 liter in a volumetric flask.

    CSK 0.0100 N KIO3 1° standard
       Wako Chemicals, Inc., 1600 Bellwood Rd., Richmond, VA  23237.


9.  References

    American Public Health Association.  1981.  Standard Methods for 
    the Examination of Water and Wastewater, 15th edition.     

    Carpenter, J. H.  1965a.  The accuracy of the Winkler method 
    for dissolved oxygen analysis.  Limnology and Oceanography, 10, 
    135-141.
     
    Carpenter, J. H.  1965b.  The Chesapeake Bay Institute technique 
    for the Winkler dissolved oxygen method. Limnology and Oceanography, 
    10, 141-143. 

    CSK Certified Seawater Reference Standards.  Sagami Chemical 
    Research Center, Sagimahara, Japan.